ALKBH8 Antibody
Produktgrößen
50ul
£316,00
OACA06810-50UL
100ul
£387,00
OACA06810-100UL
Über dieses Produkt
- SKU:
- OACA06810
- Zusätzliche Namen:
- ABH8;AlkB homologue 8;alkB; alkylation repair homolog 8;alkylated DNA repair protein alkB homolog 8;MRT71;probable alpha-ketoglutarate-dependent dioxygenase ABH8;S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8;TRM9;TRMT9;TRMT9A;tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8;tRNA methyltransferase 9 homolog;tRNA methyltransferase 9 related.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain (PubMed:20123966; PubMed:20308323). Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA (PubMed:20123966; PubMed:20308323). Has a preference for tRNA(Arg) and tRNA(Glu); and does not bind tRNA(Lys)(PubMed:20308323). Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its dioxygenase domain; giving rise to 5-(S)-methoxycarbonylhydroxymethyluridine; has a preference for tRNA(Gly) (PubMed:21285950). Required for normal survival after DNA damage (PubMed:20308323). May inhibit apoptosis and promote cell survival and angiogenesis (PubMed:19293182).
- Gendetails:
- alkB homolog 8; tRNA methyltransferase
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Alkylated DNA repair protein alkB homolog 8 protein (1-230AA)
- Isotyp:
- IgG
- Proteindetails:
- Alkylated DNA repair protein alkB homolog 8
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php