CD274 Antibody
Produktgrößen
50ul
£316,00
OACA06799-50UL
100ul
£387,00
OACA06799-100UL
Über dieses Produkt
- SKU:
- OACA06799
- Zusätzliche Namen:
- B7 homolog 1;B7-H;B7H1;CD274 antigen;hPD-L1;PDCD1 ligand 1;PDCD1L1;PDCD1LG1;PDL1;PD-L1;programmed cell death 1 ligand 1.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/CD279; modulates the activation threshold of T-cells and limits T-cell effector response (PubMed:11015443). The PDCD1/CD279-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and facilitate tumor survival (PubMed:28813417; PubMed:28813410). Through a yet unknown activating receptor; may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10) (PubMed:10581077).
- Gendetails:
- CD274 molecule
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Programmed cell death 1 ligand 1 protein (19-238AA)
- Isotyp:
- IgG
- Proteindetails:
- Programmed cell death 1 ligand 1
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php