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Antikörper

ENPP2 Antibody

Produktgrößen
50ul
£316,00
OACA06797-50UL
100ul
£387,00
OACA06797-100UL
Über dieses Produkt
SKU:
OACA06797
Zusätzliche Namen:
ATX;ATX-X;AUTOTAXIN;autotaxin-t;ectonucleotide pyrophosphatase/phosphodiesterase family member 2;E-NPP 2;extracellular lysophospholipase D;LysoPLD;NPP2;PD-IALPHA;PDNP2;phosphodiesterase I/nucleotide pyrophosphatase 2;plasma lysophospholipase D.
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Weitere Details:
Hydrolyzes lysophospholipids to produce the signaling molecule lysophosphatidic acid (LPA) in extracellular fluids (PubMed:15769751; PubMed:26371182; PubMed:27754931). Major substrate is lysophosphatidylcholine (PubMed:12176993; PubMed:27754931). Also can act on sphingosylphosphorylcholine producing sphingosine-1-phosphate; a modulator of cell motility. Can hydrolyze; in vitro; bis-pNPP; to some extent pNP-TMP; and barely ATP (PubMed:15769751; PubMed:12176993). Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation (PubMed:11559573). Stimulates migration of melanoma cells; probably via a pertussis toxin-sensitive G protein (PubMed:1733949). May have a role in induction of parturition (PubMed:12176993). Possible involvement in cell proliferation and adipose tissue development (Probable). Tumor cell motility-stimulating factor (PubMed:1733949; PubMed:11559573).
Gendetails:
ectonucleotide pyrophosphatase/phosphodiesterase 2
Host:
Rabbit
Immunogen:
Recombinant Human Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 protein (564-863AA)
Isotyp:
IgG
Proteindetails:
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
Aufreinigung:
Affinity Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C or -80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody