BNIP3 Antibody
Produktgrößen
50ul
£316,00
OACA06713-50UL
100ul
£387,00
OACA06713-100UL
Über dieses Produkt
- SKU:
- OACA06713
- Zusätzliche Namen:
- BCL2/adenovirus E1B 19 kDa protein-interacting protein 3;BCL2/adenovirus E1B 19kDa interacting protein 3;BCL2/adenovirus E1B interacting protein 3;nineteen kD interacting protein-3;NIP3.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Apoptosis-inducing protein that can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage; participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP; BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. Plays an important role in the calprotectin (S100A8/A9)-induced cell death pathway.
- Gendetails:
- BCL2 interacting protein 3
- Host:
- Rabbit
- Immunogen:
- Recombinant Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 protein (1-164AA)
- Isotyp:
- IgG
- Proteindetails:
- BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
- Aufreinigung:
- Affinity Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php