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Antikörper

CLEC4E Antibody

Produktgrößen
50ug
£305,00
OACA06458-50UG
100ug
£463,00
OACA06458-100UG
Über dieses Produkt
SKU:
OACA06458
Zusätzliche Namen:
CLECSF9;C-type (calcium dependent; carbohydrate-recognition domain) lectin; superfamily member 9;C-type lectin domain family 4 member E;C-type lectin superfamily member 9;macrophage-inducible C-type lectin;MINCLE.
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Weitere Details:
C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells; fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi; such as Candida albicans. The detection of mycobacteria is via trehalose 6;6'-dimycolate (TDM); a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130; a nuclear protein; that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein; Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK; CARD9 and NF-kappa-B.
Gendetails:
C-type lectin domain family 4 member E
Host:
Rabbit
Immunogen:
Recombinant Human C-type lectin domain family 4 member E protein (41-219AA)
Isotyp:
IgG
Proteindetails:
C-type lectin domain family 4 member E
Aufreinigung:
Protein G Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C or -80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody