EIF3C Antibody
Produktgrößen
50ug
£305,00
OACA05912-50UG
100ug
£463,00
OACA05912-100UG
Über dieses Produkt
- SKU:
- OACA05912
- Zusätzliche Namen:
- cell migration-inducing protein 17;eIF3 p110;EIF3CL;eIF3-p110;EIF3S8;eukaryotic translation initiation factor 3 subunit 8;eukaryotic translation initiation factor 3 subunit C;eukaryotic translation initiation factor 3; subunit 8 (110kD);eukaryotic translation initiation factor 3; subunit 8; 110kDa.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Component of the eukaryotic translation initiation factor 3 (eIF-3) complex; which is required for several steps in the initiation of protein synthesis (PubMed:17581632; PubMed:25849773; PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1; eIF-1A; eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation; including cell cycling; differentiation and apoptosis; and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
- Gendetails:
- eukaryotic translation initiation factor 3 subunit C
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Eukaryotic translation initiation factor 3 subunit C protein (201-500AA)
- Isotyp:
- IgG
- Proteindetails:
- Eukaryotic translation initiation factor 3 subunit C
- Reinheit:
- >95%
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php