CNDP2 Antibody
Produktgrößen
50ug
£305,00
OACA05903-50UG
100ug
£463,00
OACA05903-100UG
Über dieses Produkt
- SKU:
- OACA05903
- Zusätzliche Namen:
- carnosinase-2;carnosine dipeptidase II;CN2;CNDP dipeptidase 2;CNDP dipeptidase 2 (metallopeptidase M20 family);CPGL;cytosolic nonspecific dipeptidase;cytosolic non-specific dipeptidase;epididymis secretory protein Li 13;glutamate carboxypeptidase-like protein 1;HEL-S-13;HsT2298;PEPA;peptidase A.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly (PubMed:19346245). Acts as a functional tumor suppressor in gastric cancer via activation of the mitogen-activated protein kinase (MAPK) pathway. An elevated level of CNDP2 activates the p38 and JNK MAPK pathways to induce cell apoptosis; and a lower level of CNDP2 activates the ERK MAPK pathway to promote cell proliferation (PubMed:24395568). Isoform 2 may play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells (PubMed:17121880). Catalyzes the production of N-lactoyl-amino acids from lactate and amino acids by reverse proteolysis (PubMed:25964343).
- Gendetails:
- carnosine dipeptidase 2
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Cytosolic non-specific dipeptidase protein (2-475AA)
- Isotyp:
- IgG
- Proteindetails:
- Cytosolic non-specific dipeptidase
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php