CEP63 Antibody
Produktgrößen
50ug
£305,00
OACA05550-50UG
100ug
£463,00
OACA05550-100UG
Über dieses Produkt
- SKU:
- OACA05550
- Zusätzliche Namen:
- centrosomal protein 63kDa;centrosomal protein of 63 kDa;centrosome protein CEP63;SCKL6.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152; CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. Reported to be required for centrosomal recruitment of CEP152; however; this function has been questioned (PubMed:21983783; PubMed:26297806). Also recruits CDK1 to centrosomes (PubMed:21406398). Plays a role in DNA damage response. Following DNA damage; such as double-strand breaks (DSBs); is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression (PubMed:21406398).
- Gendetails:
- centrosomal protein 63
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Centrosomal protein of 63 kDa protein (1-495AA)
- Isotyp:
- IgG
- Proteindetails:
- Centrosomal protein of 63 kDa
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php