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Antikörper

DIS3L2 Antibody

Produktgrößen
50ug
£305,00
OACA05332-50UG
100ug
£463,00
OACA05332-100UG
Über dieses Produkt
SKU:
OACA05332
Zusätzliche Namen:
DIS3 mitotic control homolog-like 2;DIS3-like exonuclease 2;FAM6A;family with sequence similarity 6; member A;hDIS3L2;PRLMNS.
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Weitere Details:
3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase; such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs; contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis; and negatively regulates cell proliferation.
Gendetails:
DIS3 like 3'-5' exoribonuclease 2
Host:
Rabbit
Immunogen:
Recombinant Human DIS3-like exonuclease 2 protein (201-400AA)
Isotyp:
IgG
Proteindetails:
DIS3-like exonuclease 2
Aufreinigung:
Protein G Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C or -80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody