ATXN7L3 Antibody
Produktgrößen
50ug
£305,00
OACA04690-50UG
100ug
£463,00
OACA04690-100UG
Über dieses Produkt
- SKU:
- OACA04690
- Zusätzliche Namen:
- ataxin-7-like protein 3;SAGA-associated factor 11 homolog;SGF11.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Component of the transcription regulatory histone acetylation (HAT) complex SAGA; a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex; participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B (PubMed:18206972; PubMed:21746879). The SAGA complex is recruited to specific gene promoters by activators such as MYC; where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex; it is required to recruit USP22 and ENY2 into the SAGA complex (PubMed:18206972). Regulates H2B monoubiquitination (H2Bub1) levels. Affects subcellular distribution of ENY2; USP22 and ATXN7L3B (PubMed:27601583).
- Gendetails:
- ataxin 7 like 3
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Ataxin-7-like protein 3 protein (51-347AA)
- Isotyp:
- IgG
- Proteindetails:
- Ataxin-7-like protein 3
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php