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Antikörper

GTF2H5 Antibody

Produktgrößen
50ug
£305,00
OACA03082-50UG
100ug
£463,00
OACA03082-100UG
Über dieses Produkt
SKU:
OACA03082
Zusätzliche Namen:
bA120J8.2;C6orf175;General transcription factor IIH polypeptide 5;general transcription factor IIH subunit 5;general transcription factor IIH; polypeptide 5;TFB5;TFB5 ortholog;TFIIH;TFIIH basal transcription factor complex TTDA subunit;TFIIH basal transcription factor complex TTD-A subunit;TFIIH subunit p8;TGF2H5;TTD;TTD3;TTDA;TTD-A.
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Weitere Details:
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex; which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and; when complexed to CAK; in RNA transcription by RNA polymerase II. In NER; TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription; TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established; TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription. Necessary for the stability of the TFIIH complex and for the presence of normal levels of TFIIH in the cell.
Gendetails:
general transcription factor IIH subunit 5
Host:
Rabbit
Immunogen:
Recombinant Human General transcription factor IIH subunit 5 protein (1-71AA)
Isotyp:
IgG
Proteindetails:
General transcription factor IIH subunit 5
Aufreinigung:
Protein G Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C or -80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody