GRK2 Antibody
Produktgrößen
50ug
£305,00
OACA03053-50UG
100ug
£463,00
OACA03053-100UG
Über dieses Produkt
- SKU:
- OACA03053
- Zusätzliche Namen:
- ADRBK1;adrenergic beta receptor kinase 1;BARK1;beta-adrenergic receptor kinase 1;beta-ARK-1;BETA-ARK1;G-protein coupled receptor kinase 2.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors; probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner (PubMed:19306925; PubMed:19715378). Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by faciltating the trafficking of SMO into the cilium and the stimulation of SMO activity (By similarity).
- Gendetails:
- G protein-coupled receptor kinase 2
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Beta-adrenergic receptor kinase 1 protein (2-221AA)
- Isotyp:
- IgG
- Proteindetails:
- Beta-adrenergic receptor kinase 1
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php