EYA2 Antibody
Produktgrößen
50ug
£305,00
OACA02933-50UG
100ug
£463,00
OACA02933-100UG
Über dieses Produkt
- SKU:
- OACA02933
- Zusätzliche Namen:
- EAB1;eyes absent homolog 2.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Functions both as protein phosphatase and as transcriptional coactivator for SIX1; and probably also for SIX2; SIX4 and SIX5 (PubMed:12500905; PubMed:23435380). Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress (PubMed:19351884). Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2; in this it is functionally redundant with EYA1 (PubMed:12500905).
- Gendetails:
- EYA transcriptional coactivator and phosphatase 2
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Eyes absent homolog 2 protein (1-514AA)
- Isotyp:
- IgG
- Proteindetails:
- Eyes absent homolog 2
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php