ETHE1 Antibody
Produktgrößen
50ug
£305,00
OACA02928-50UG
100ug
£463,00
OACA02928-100UG
Über dieses Produkt
- SKU:
- OACA02928
- Zusätzliche Namen:
- ethylmalonic encephalopathy 1;Ethylmalonic encephalopathy protein 1;hepatoma subtracted clone one protein;HSCO;persulfide dioxygenase ETHE1; mitochondrial;protein ETHE1; mitochondrial;sulfur dioxygenase ETHE1;YF13H12.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H(2)S) is first oxidized by SQRDL; giving rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide; once it has been transferred to a thiophilic acceptor; such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H(2)S levels that have toxic effects; due to the inhibition of cytochrome c oxidase. First described as a protein that can shuttle between the nucleus and the cytoplasm and suppress p53-induced apoptosis by sequestering the transcription factor RELA/NFKB3 in the cytoplasm and preventing its accumulation in the nucleus (PubMed:12398897).
- Gendetails:
- ETHE1 persulfide dioxygenase
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Persulfide dioxygenase ETHE1; mitochondrial protein (8-254AA)
- Isotyp:
- IgG
- Proteindetails:
- Persulfide dioxygenase ETHE1; mitochondrial
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php