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Antikörper

DNAJB2 Antibody

Produktgrößen
50ug
£305,00
OACA02863-50UG
100ug
£463,00
OACA02863-100UG
Über dieses Produkt
SKU:
OACA02863
Zusätzliche Namen:
CMT2T;DnaJ (Hsp40) homolog; subfamily B; member 2;dnaJ homolog subfamily B member 2;dnaJ protein homolog 1;DSMA5;heat shock 40 kDa protein 3;heat shock protein J1;heat shock protein; neuronal DNAJ-like 1;HSJ1;HSJ-1;HSPF3.
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Weitere Details:
Functions as a co-chaperone; regulating the substrate binding and activating the ATPase activity of chaperones of the HSP70/heat shock protein 70 family (PubMed:7957263; PubMed:22219199). In parallel; also contributes to the ubiquitin-dependent proteasomal degradation of misfolded proteins (PubMed:15936278; PubMed:21625540). Thereby; may regulate the aggregation and promote the functional recovery of misfolded proteins like HTT; MC4R; PRKN; RHO and SOD1 and be crucial for many biological processes (PubMed:12754272; PubMed:20889486; PubMed:21719532; PubMed:22396390; PubMed:24023695). Isoform 1 which is localized to the endoplasmic reticulum membranes may specifically function in ER-associated protein degradation of misfolded proteins (PubMed:15936278).
Gendetails:
DnaJ heat shock protein family (Hsp40) member B2
Host:
Rabbit
Immunogen:
Recombinant Human DnaJ homolog subfamily B member 2 protein (2-324AA)
Isotyp:
IgG
Proteindetails:
DnaJ homolog subfamily B member 2
Aufreinigung:
Protein G Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C or -80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody