CXADR Antibody
Produktgrößen
50ug
£305,00
OACA02815-50UG
100ug
£463,00
OACA02815-100UG
Über dieses Produkt
- SKU:
- OACA02815
- Zusätzliche Namen:
- 46 kD coxsackievirus and adenovirus receptor (CAR) protein;CAR;CAR4/6;coxsackie virus and adenovirus receptor;coxsackievirus and adenovirus receptor;coxsackievirus B-adenovirus receptor;CVB3-binding protein;HCAR;HCVADR.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells; a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding; JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.
- Gendetails:
- CXADR Ig-like cell adhesion molecule
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Coxsackievirus and adenovirus receptor protein (259-365AA)
- Isotyp:
- IgG
- Proteindetails:
- Coxsackievirus and adenovirus receptor
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php