CLASP2 Antibody
Produktgrößen
50ug
£305,00
OACA02752-50UG
100ug
£463,00
OACA02752-100UG
Über dieses Produkt
- SKU:
- OACA02752
- Zusätzliche Namen:
- CLIP-associating protein 2;CLIP-associating protein CLASP2;Cytoplasmic linker-associated protein 2;multiple asters (Mast)-like homolog 2;protein Orbit homolog 2.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules (PubMed:26003921). Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2 (PubMed:16824950). This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle (PubMed:16866869; PubMed:16914514). Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.
- Gendetails:
- cytoplasmic linker associated protein 2
- Host:
- Rabbit
- Immunogen:
- Recombinant Human CLIP-associating protein 2 protein (226-381AA)
- Isotyp:
- IgG
- Proteindetails:
- CLIP-associating protein 2
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php