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Antikörper

BLOC1S1 Antibody

Produktgrößen
50ug
£305,00
OACA02723-50UG
100ug
£463,00
OACA02723-100UG
Über dieses Produkt
SKU:
OACA02723
Zusätzliche Namen:
biogenesis of lysosome-related organelles complex 1 subunit 1;BLOC-1 subunit 1;BLOS1;BORCS1;GCN5 (general control of amino-acid synthesis; yeast; homolog)-like 1;GCN5 general control of amino-acid synthesis 5-like 1;GCN5L1;GCN5-like protein 1;MICoA;MTA1-interacting coactivator;Protein RT14;RT14.
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Weitere Details:
Component of the BLOC-1 complex; a complex that is required for normal biogenesis of lysosome-related organelles (LRO); such as platelet dense granules and melanosomes. In concert with the AP-3 complex; the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex; in association with SNARE proteins; is also proposed to be involved in neurite extension (PubMed:17182842). As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes; the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed:25898167).
Gendetails:
biogenesis of lysosomal organelles complex 1 subunit 1
Host:
Rabbit
Immunogen:
Recombinant Human Biogenesis of lysosome-related organelles complex 1 subunit 1 protein (1-153AA)
Isotyp:
IgG
Proteindetails:
Biogenesis of lysosome-related organelles complex 1 subunit 1
Aufreinigung:
Protein G Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C or -80Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody