GDF15 Antibody
Produktgrößen
50ug
£366,00
OACA02491-50UG
100ug
£532,00
OACA02491-100UG
Über dieses Produkt
- SKU:
- OACA02491
- Zusätzliche Namen:
- GDF-15;growth/differentiation factor 15;macrophage inhibitory cytokine 1;MIC1;MIC-1;NAG-1;non-steroidal anti-inflammatory drug-activated gene-1;NRG-1;NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1;NSAID-activated gene 1 protein;NSAID-regulated gene 1 protein;PDF;PLAB;placental bone morphogenetic protein;placental TGF-beta;prostate differentiation factor;PTGFB;PTGF-beta.
- Klonalität:
- Monoclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- Regulates food intake; energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886; PubMed:28846097; PubMed:28846098; PubMed:28846099; PubMed:23468844; PubMed:29046435). Binds to its receptor; GFRAL; and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem (PubMed:28953886; PubMed:28846097; PubMed:28846098; PubMed:28846099). It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala; which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (PubMed:28953886). On hepatocytes; inhibits growth hormone signaling (By similarity).
- Gendetails:
- growth differentiation factor 15
- Host:
- Mouse
- Immunogen:
- Recombinant GDF15 Protein
- Isotyp:
- IgG2a
- Proteindetails:
- Growth/differentiation factor 15
- Reinheit:
- >95%
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php