COBRA1 Antibody - Biotin Conjugated
Produktgrößen
100ug
£478,00
OACA01107-100UG
Über dieses Produkt
- SKU:
- OACA01107
- Zusätzliche Namen:
- COBRA1;cofactor of BRCA1;negative elongation factor B;negative elongation factor protein B;NELF-B.
- Klonalität:
- Polyclonal
- Konjugat:
- Biotin
- Weitere Details:
- Essential component of the NELF complex; a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex; which acts via an association with the DSIF complex and causes transcriptional pausing; is counteracted by the P-TEFb kinase complex. The NELF complex is involved in HIV-1 latency possibly involving recruitment of PCF11 to paused RNA polymerase II. Binds RNA which may help to stabilize the NELF complex on nucleic acid. In vitro; binds weakly to the HIV-1 TAR RNA which is located in the long terminal repeat (LTR) of HIV-1. May be able to induce chromatin unfolding.
- Gendetails:
- negative elongation factor complex member B
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Negative elongation factor B protein (8-199AA)
- Isotyp:
- IgG
- Proteindetails:
- Negative elongation factor B
- Reinheit:
- Caprylic Acid Ammonium Sulfate Precipitation
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php