Eno1 Antibody - HRP Conjugated
Produktgrößen
100ug
£478,00
OACA00443-100UG
Über dieses Produkt
- SKU:
- OACA00443
- Zusätzliche Namen:
- b;BMP-14;bone morphogenetic protein 14;bp;brp;cartilage-derived morphogenetic protein-1;CDMP-;Cdmp-1;growth/differentiation factor 5.
- Klonalität:
- Polyclonal
- Konjugat:
- HRP
- Weitere Details:
- Growth factor involved in bone and cartilage formation. During cartilage development regulates differentiation of chondrogenic tissue through two pathways. Firstly; positively regulates differentiation of chondrogenic tissue through its binding of high affinity with BMPR1B and of less affinity with BMPR1A; leading to induction of SMAD1-SMAD5-SMAD8 complex phosphorylation and then SMAD protein signaling transduction (By similarity). Secondly; negatively regulates chondrogenic differentiation through its interaction with NOG (By similarity). Required to prevent excessive muscle loss upon denervation. This function requires SMAD4 and is mediated by phosphorylated SMAD1/5/8 (PubMed:24076600). Binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response; including TNF secretion by monocytes (By similarity).
- Gendetails:
- growth differentiation factor 5
- Host:
- Rabbit
- Immunogen:
- Recombinant Mouse Growth/differentiation factor 5 protein (376-495AA)
- Isotyp:
- IgG
- Proteindetails:
- Growth/differentiation factor 5
- Reinheit:
- Caprylic Acid Ammonium Sulfate Precipitation purified
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php