DNMT3A Antibody - HRP Conjugated
Produktgrößen
100ug
£478,00
OACA00371-100UG
Über dieses Produkt
- SKU:
- OACA00371
- Zusätzliche Namen:
- cysteine methyltransferase DNMT3A;DNA (cytosine-5-)-methyltransferase 3 alpha;DNA (cytosine-5)-methyltransferase 3A;DNA cytosine methyltransferase 3A2;DNA methyltransferase HsaIIIA;DNA MTase HsaIIIA;DNMT3A2;HESJAS;M.HsaIIIA;TBRS.
- Klonalität:
- Polyclonal
- Konjugat:
- HRP
- Weitere Details:
- Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZBTB18. Recruited to trimethylated 'Lys-36' of histone H3 (H3K36me3) sites. Can actively repress transcription through the recruitment of HDAC activity.
- Gendetails:
- DNA methyltransferase 3 alpha
- Host:
- Rabbit
- Immunogen:
- Recombinant Human DNA (cytosine-5)-methyltransferase 3A protein (680-902AA)
- Isotyp:
- IgG
- Proteindetails:
- DNA (cytosine-5)-methyltransferase 3A
- Reinheit:
- Caprylic Acid Ammonium Sulfate Precipitation purified
- Aufreinigung:
- Protein G Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C or -80Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php