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Antikörper

CDC14B Antibody

Produktgrößen
100ul
£597,00
OABF01807-100UL
Über dieses Produkt
SKU:
OABF01807
Zusätzliche Namen:
CDC14 cell division cycle 14 homolog B;Cdc14B1;Cdc14B2;CDC14B3;dual specificity protein phosphatase CDC14B;hCDC14B.
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Konzentration:
1 ug/ul
Weitere Details:
Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage; translocates to the nucleus and dephosphorylates FZR1/CDH1; a key activator of the anaphase promoting complex/cyclosome (APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C; leading to the ubiquitination of PLK1; preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases.
Gendetails:
cell division cycle 14B
Host:
Rabbit
Immunogen:
KLH conjugated synthetic peptide derived from human CDC14B
Isotyp:
IgG
Proteindetails:
Dual specificity protein phosphatase CDC14B
Aufreinigung:
Protein A Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody