CHAC1 Antibody
Produktgrößen
100ul
£597,00
OABF01753-100UL
Über dieses Produkt
- SKU:
- OABF01753
- Zusätzliche Namen:
- blocks Notch protein;botch;Cation transport regulator-like protein 1;ChaC; cation transport regulator homolog 1;ChaC; cation transport regulator-like 1;gamma-GCG 1;gamma-GCT acting on glutathione homolog 1;glutathione-specific gamma-glutamylcyclotransferase 1.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 1 ug/ul
- Weitere Details:
- Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione; but not on other gamma-glutamyl peptides (PubMed:27913623). Glutathione depletion is an important factor for apoptosis initiation and execution. Acts as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade (PubMed:19109178). Negative regulator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting Notch cleavage by furin; maintaining Notch in an immature inactive form; thereby promoting neurogenesis in embryos (PubMed:22445366).
- Gendetails:
- ChaC glutathione specific gamma-glutamylcyclotransferase 1
- Host:
- Rabbit
- Immunogen:
- KLH conjugated synthetic peptide derived from human CHAC1
- Isotyp:
- IgG
- Proteindetails:
- Glutathione-specific gamma-glutamylcyclotransferase 1
- Aufreinigung:
- Protein A Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php