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Antikörper

CH25H Antibody

Produktgrößen
100ul
£597,00
OABF01697-100UL
Über dieses Produkt
SKU:
OABF01697
Zusätzliche Namen:
C25H;cholesterol 25-hydroxylase;cholesterol 25-monooxygenase;h25OH.
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Konzentration:
1 ug/ul
Weitere Details:
Catalyzes the formation of 25-hydroxycholesterol from cholesterol; leading to repress cholesterol biosynthetic enzymes (PubMed:9852097). Plays a key role in cell positioning and movement in lymphoid tissues: 25-hydroxycholesterol is an intermediate in biosynthesis of 7-alpha;25-dihydroxycholesterol (7-alpha;25-OHC); an oxysterol that acts as a ligand for the G protein-coupled receptor GPR183/EBI2; a chemotactic receptor for a number of lymphoid cells. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis; production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.
Gendetails:
cholesterol 25-hydroxylase
Host:
Rabbit
Immunogen:
KLH conjugated synthetic peptide derived from human CH25H
Isotyp:
IgG
Molekulargewicht:
32 kDa
Proteindetails:
Cholesterol 25-hydroxylase
Aufreinigung:
Protein A Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody