FZD7 Antibody
Produktgrößen
100ul
£597,00
OABF01524-100UL
Über dieses Produkt
- SKU:
- OABF01524
- Zusätzliche Namen:
- frizzled 7; seven transmembrane spanning receptor;frizzled family receptor 7;frizzled homolog 7;Frizzled; drosophila; homolog of; 7;frizzled-7;fz-7;FzE3;hFz7.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 1 ug/ul
- Weitere Details:
- Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway; which leads to the activation of disheveled proteins; inhibition of GSK-3 kinase; nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members; but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway; as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
- Gendetails:
- frizzled class receptor 7
- Host:
- Rabbit
- Immunogen:
- KLH conjugated synthetic peptide derived from human Frizzled 7
- Isotyp:
- IgG
- Proteindetails:
- Frizzled-7
- Aufreinigung:
- Protein A Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php