ENG Antibody
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100ul
£597,00
OABF01460-100UL
Über dieses Produkt
- SKU:
- OABF01460
- Zusätzliche Namen:
- CD105 antigen;END;endoglin;HHT1;ORW1.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 1 ug/ul
- Weitere Details:
- Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis (PubMed:21737454; PubMed:23300529). Required for normal structure and integrity of adult vasculature (PubMed:7894484). Regulates the migration of vascular endothelial cells (PubMed:17540773). Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity). May regulate endothelial cell shape changes in response to blood flow; which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (By similarity). May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors (PubMed:1692830). Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade that ultimately leads to the activation of SMAD transcription factors (PubMed:8370410; PubMed:21737454; PubMed:22347366; PubMed:23300529). Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGFB1 signaling through SMAD3 (PubMed:21737454; PubMed:22347366; PubMed:23300529).
- Gendetails:
- endoglin
- Host:
- Rabbit
- Immunogen:
- KLH conjugated synthetic peptide derived from human CD105
- Isotyp:
- IgG
- Proteindetails:
- Endoglin
- Aufreinigung:
- Protein A Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php