EIF3A Antibody
Produktgrößen
100ul
£597,00
OABF01336-100UL
Über dieses Produkt
- SKU:
- OABF01336
- Zusätzliche Namen:
- centrosomin homolog;cytoplasmic protein p167;EIF3;eIF3 p167;eIF3 p180;eIF3 p185;EIF3; p180 subunit;eIF3-p170;EIF3S10;eIF3-theta;eIF-3-theta;eukaryotic translation initiation factor 3 subunit 10;eukaryotic translation initiation factor 3 subunit A;eukaryotic translation initiation factor 3; subunit 10 (theta; 150/170kD);eukaryotic translation initiation factor 3; subunit 10 (theta; 170kD);eukaryotic translation initiation factor 3; subunit 10 theta; 150/170kDa;eukaryotic translation initiation factor 3; subunit 10; 170kD;P167;p180;p185;TIF32.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 1 ug/ul
- Weitere Details:
- RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex; which is required for several steps in the initiation of protein synthesis (PubMed:17581632; PubMed:25849773). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1; eIF-1A; eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632; PubMed:11169732). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation; including cell cycling; differentiation and apoptosis; and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773; PubMed:27462815).
- Gendetails:
- eukaryotic translation initiation factor 3 subunit A
- Host:
- Rabbit
- Immunogen:
- KLH conjugated synthetic peptide derived from human eIF3A
- Isotyp:
- IgG
- Proteindetails:
- Eukaryotic translation initiation factor 3 subunit A
- Aufreinigung:
- Protein A Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php