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Antikörper

DKK3 Antibody

Produktgrößen
100ul
£597,00
OABF01067-100UL
Über dieses Produkt
SKU:
OABF01067
Zusätzliche Namen:
dickkopf 3 homolog;dickkopf homolog 3;dickkopf-3;dickkopf-related protein 3;dkk-3;hDkk-3;regulated in glioma;REIC;RIG;RIG-like 5-6;RIG-like 7-1.
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Konzentration:
1 ug/ul
Weitere Details:
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development; where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning; limb development; somitogenesis and eye formation. In the adult; Dkks are implicated in bone formation and bone disease; cancer and Alzheimer disease (By similarity).
Gendetails:
dickkopf WNT signaling pathway inhibitor 3
Host:
Rabbit
Immunogen:
KLH conjugated synthetic peptide derived from human DKK3
Isotyp:
IgG
Proteindetails:
Dickkopf-related protein 3
Aufreinigung:
Protein A Purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20Â[o]C
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody