CD6 Antibody
Produktgrößen
100ul
£597,00
OABF00990-100UL
Über dieses Produkt
- SKU:
- OABF00990
- Zusätzliche Namen:
- CD6 antigen;T12;T-cell differentiation antigen CD6;TP120.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 1 ug/ul
- Weitere Details:
- Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166 (PubMed:15048703; PubMed:15294938; PubMed:16352806; PubMed:16914752; PubMed:24945728; PubMed:24584089). Contributes to signaling cascades triggered by activation of the TCR/CD3 complex (PubMed:24584089). Functions as costimulatory molecule; promotes T-cell activation and proliferation (PubMed:15294938; PubMed:16352806; PubMed:16914752). Contributes to the formation and maturation of the immunological synapse (PubMed:15294938; PubMed:16352806). Functions as calcium-dependent pattern receptor that binds and aggregates both Gram-positive and Gram-negative bacteria. Binds both lipopolysaccharide (LPS) from Gram-negative bacteria and lipoteichoic acid from Gram-positive bacteria (PubMed:17601777). LPS binding leads to the activation of signaling cascades and down-stream MAP kinases (PubMed:17601777). Mediates activation of the inflammatory response and the secretion of pro-inflammatory cytokines in response to LPS (PubMed:17601777).
- Gendetails:
- CD6 molecule
- Host:
- Rabbit
- Immunogen:
- KLH conjugated synthetic peptide derived from human CD6
- Isotyp:
- IgG
- Proteindetails:
- T-cell differentiation antigen CD6
- Aufreinigung:
- Protein A Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php