DISP2 Antibody
Produktgrößen
100ul
£597,00
OABF00522-100UL
Über dieses Produkt
- SKU:
- OABF00522
- Zusätzliche Namen:
- C15orf36;dispatched B;DISPB;HsT16908;LINC00594;long intergenic non-protein coding RNA 594;protein dispatched homolog 2.
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 1 ug/ul
- Weitere Details:
- DISP2 is the second of three known homologs of the D.melanogaster protein Dispatched. It is a multitransmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored Hedgehog from producing cells. Hedgehog is a major player in signaling pathways during embryogenesis; tissue regeneration; and carcinogenesis and the DISP proteins have been implicated in these pathways. Recently; it has been shown that DISP2 is translationally regulated by the microRNA miR-214 in zebrafish. Expression of this miRNA decreased DISP2 promoter activity in vitro and its overexpression in zebrafish resulted in a phenotype identical to that observed by DISP2 mutants. At least two isoforms of DISP2 are known to exist.
- Gendetails:
- dispatched RND transporter family member 2
- Host:
- Rabbit
- Immunogen:
- KLH conjugated synthetic peptide derived from human DISP2
- Isotyp:
- IgG
- Proteindetails:
- Protein dispatched homolog 2
- Aufreinigung:
- Protein A Purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20Â[o]C
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php