ETHE1 Antibody
Produktgrößen
50ul
£264,00
OAAN04148-50UL
100ul
£379,00
OAAN04148-100UL
200ul
£581,00
OAAN04148-200UL
Über dieses Produkt
- SKU:
- OAAN04148
- Zusätzliche Namen:
- HSCO; YF13H12
- Klonalität:
- Polyclonal
- Weitere Details:
- Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H2S) is first oxidized by SQRDL; giving rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide; once it has been transferred to a thiophilic acceptor; such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H2S levels that have toxic effects; due to the inhibition of cytochrome c oxidase. First described as a protein that can shuttle between the nucleus and the cytoplasm and suppress p53-induced apoptosis by sequestering the transcription factor RELA/NFKB3 in the cytoplasm and preventing its accumulation in the nucleus.
- Gendetails:
- ETHE1; persulfide dioxygenase
- Host:
- Rabbit
- Immunogen:
- Recombinant Protein
- Isotyp:
- IgG
- Molekulargewicht:
- 28 kDa
- Proteindetails:
- Clustered mitochondria protein homolog
- Aufreinigung:
- Affinity purification
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at +4C. For long term storage; aliquote and store at -20C. Avoid freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php