CST3 Antibody
Produktgrößen
50ul
£264,00
OAAN03238-50UL
100ul
£379,00
OAAN03238-100UL
200ul
£581,00
OAAN03238-200UL
Über dieses Produkt
- SKU:
- OAAN03238
- Zusätzliche Namen:
- ARMD11; HEL-S-2
- Klonalität:
- Polyclonal
- Weitere Details:
- The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors; while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily; including the type 1 cystatins (stefins); type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions; where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases; which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions; establishing its role in vascular disease. In addition; this protein has been shown to have an antimicrobial function; inhibiting the replication of herpes simplex virus. Alternative splicing results in multiple transcript variants encoding a single protein.
- Gendetails:
- cystatin C
- Host:
- Rabbit
- Immunogen:
- Recombinant Protein
- Isotyp:
- IgG
- Molekulargewicht:
- 16 kDa
- Proteindetails:
- Collagen alpha-1(II) chain
- Aufreinigung:
- Affinity purification
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at +4C. For long term storage; aliquote and store at -20C. Avoid freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php