AR Antibody
Produktgrößen
50ul
£321,00
OAAN02941-50UL
100ul
£479,00
OAAN02941-100UL
200ul
£708,00
OAAN02941-200UL
Über dieses Produkt
- SKU:
- OAAN02941
- Zusätzliche Namen:
- KD; AIS; AR8; TFM; DHTR; SBMA; HYSP1; NR3C4; SMAX1; HUMARA
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Konzentration:
- 0.5 mg/ml
- Weitere Details:
- The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain; DNA-binding domain; and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand; the receptor dissociates from accessory proteins; translocates into the nucleus; dimerizes; and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described.
- Gendetails:
- androgen receptor
- Host:
- Rabbit
- Immunogen:
- A phospho-Serpecific peptide corresponding-Thro residues-Serurrounding-Ser213 of human AR
- Isotyp:
- IgG
- Molekulargewicht:
- 110 kDa
- Proteindetails:
- Androgen receptor
- Aufreinigung:
- Affinity purified against immunogen
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php