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Antikörper

ERBB4 Antibody

Produktgrößen
50ul
£321,00
OAAN02733-50UL
100ul
£479,00
OAAN02733-100UL
200ul
£708,00
OAAN02733-200UL
Über dieses Produkt
SKU:
OAAN02733
Zusätzliche Namen:
HER4; ALS19; p180erbB4
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Weitere Details:
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains; a transmembrane domain; a tyrosine kinase domain; a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however; not all variants have been fully characterized.
Gendetails:
erb-b2 receptor tyrosine kinase 4
Host:
Rabbit
Immunogen:
A phospho-Serpecific peptide corresponding-Thro residues-Serurrounding-Tyr1284 of human HER4
Isotyp:
IgG
Proteindetails:
Receptor tyrosine-protein kinase erbB-4
Aufreinigung:
Affinity purified against immunogen
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at -20C. Avoid repeated freeze/thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody