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Antikörper

C5 Antibody

Produktgrößen
50ul
£264,00
OAAN02597-50UL
100ul
£379,00
OAAN02597-100UL
200ul
£581,00
OAAN02597-200UL
Über dieses Produkt
SKU:
OAAN02597
Zusätzliche Namen:
C5D; C5a; C5b; ECLZB; CPAMD4
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Weitere Details:
This gene encodes a component of the complement system; a part of the innate immune system that plays an important role in inflammation; host homeostasis; and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products; including the C5 alpha chain; C5 beta chain; C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains; which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin; which possesses potent spasmogenic and chemotactic activity; and the C5b macromolecular cleavage product; a subunit of the membrane attack complex (MAC). Mutations in this gene cause complement component 5 deficiency; a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants.
Gendetails:
complement component 5
Host:
Rabbit
Immunogen:
Recombinant protein of human C5
Isotyp:
IgG
Molekulargewicht:
188 kDa
Proteindetails:
Complement C5
Aufreinigung:
Affinity purified against immunogen
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at -20C. Avoid repeated freeze/thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody