CHRFAM7A Antibody
Produktgrößen
50ul
£264,00
OAAN02465-50UL
100ul
£379,00
OAAN02465-100UL
200ul
£581,00
OAAN02465-200UL
Über dieses Produkt
- SKU:
- OAAN02465
- Zusätzliche Namen:
- D-10; CHRNA7; NACHRA7; CHRNA7-DR1
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7; which is located on chromosome 15 in a region associated with several neuropsychiatric disorders; is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed; and two variants exist; for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene; translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.
- Gendetails:
- CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion
- Host:
- Rabbit
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human CHRFAM7A (NP_647536.1).
- Isotyp:
- IgG
- Molekulargewicht:
- 46 kDa
- Proteindetails:
- CHRNA7-FAM7A fusion protein
- Aufreinigung:
- Affinity purified against immunogen
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20°C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php