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Antikörper

GPI Antibody

Produktgrößen
50ul
£264,00
OAAN02052-50UL
100ul
£379,00
OAAN02052-100UL
200ul
£581,00
OAAN02052-200UL
Über dieses Produkt
SKU:
OAAN02052
Zusätzliche Namen:
AMF; NLK; PGI; PHI; GNPI; SA36; SA-36
Klonalität:
Polyclonal
Weitere Details:
This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm; the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phophsate and fructose-6-phosphate. Extracellularly; the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons; and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis; immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants.
Gendetails:
glucose-6-phosphate isomerase
Host:
Rabbit
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human GPI (NP_000166.2).
Isotyp:
IgG
Molekulargewicht:
63 kDa
Proteindetails:
Glucose-6-phosphate isomerase
Aufreinigung:
Affinity purified
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at -20C. Avoid repeated freeze/thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody