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Antikörper

ATP6V1B1 Antibody

Produktgrößen
50ul
£264,00
OAAN02034-50UL
100ul
£379,00
OAAN02034-100UL
200ul
£581,00
OAAN02034-200UL
Über dieses Produkt
SKU:
OAAN02034
Zusätzliche Namen:
VATB; VMA2; VPP3; DRTA2; RTA1B; ATP6B1
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Weitere Details:
This gene encodes a component of vacuolar ATPase (V-ATPase); a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting; zymogen activation; receptor-mediated endocytosis; and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits; two G subunits plus the C; D; E; F; and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a; c; c'; c''; and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness.
Gendetails:
ATPase H+ transporting V1 subunit B1
Host:
Rabbit
Immunogen:
Recombinant protein of human ATP6V1B1
Isotyp:
IgG
Molekulargewicht:
57 kDa
Proteindetails:
V-type proton ATPase subunit B; kidney isoform
Aufreinigung:
Affinity purified against immunogen
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at -20C. Avoid repeated freeze/thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody