GALE Antibody
Produktgrößen
50ul
£264,00
OAAN01892-50UL
100ul
£379,00
OAAN01892-100UL
200ul
£581,00
OAAN01892-200UL
Über dieses Produkt
- SKU:
- OAAN01892
- Zusätzliche Namen:
- SDR1E1
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose; and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose; but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia; also referred to as galactosemia type 3; a disease characterized by liver damage; early-onset cataracts; deafness and mental retardation; with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified.
- Gendetails:
- UDP-galactose-4-epimerase
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human GALE
- Isotyp:
- IgG
- Molekulargewicht:
- 38 kDa
- Proteindetails:
- UDP-glucose 4-epimerase
- Aufreinigung:
- Affinity purified against immunogen
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php