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Antikörper

CCM2 Antibody

Produktgrößen
50ul
£264,00
OAAN01866-50UL
100ul
£379,00
OAAN01866-100UL
200ul
£581,00
OAAN01866-200UL
Über dieses Produkt
SKU:
OAAN01866
Zusätzliche Namen:
OSM; C7orf22; PP10187
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Weitere Details:
This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure; cell-cell interactions; and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.
Gendetails:
CCM2 scaffolding protein
Host:
Rabbit
Immunogen:
Recombinant protein of human CCM2
Isotyp:
IgG
Molekulargewicht:
49 kDa
Proteindetails:
Cerebral cavernous malformations 2 protein
Aufreinigung:
Affinity purified against immunogen
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at -20C. Avoid repeated freeze/thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody