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Antikörper

FDPS Antibody

Produktgrößen
50ul
£264,00
OAAN01492-50UL
100ul
£379,00
OAAN01492-100UL
200ul
£581,00
OAAN01492-200UL
Über dieses Produkt
SKU:
OAAN01492
Zusätzliche Namen:
FPS; FPPS; POROK9
Klonalität:
Polyclonal
Konjugat:
Unconjugated
Weitere Details:
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product; farnesyl pyrophosphate; is a key intermediate in cholesterol and sterol biosynthesis; a substrate for protein farnesylation and geranylgeranylation; and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1; 7; 14; 15; 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.
Gendetails:
farnesyl diphosphate synthase
Host:
Rabbit
Immunogen:
Recombinant protein of human FDPS
Isotyp:
IgG
Molekulargewicht:
48 kDa
Proteindetails:
Farnesyl pyrophosphate synthase
Aufreinigung:
Affinity purified against immunogen
Versandbedingungen:
Blue Ice
Lagerbedingungen:
Store at -20C. Avoid repeated freeze/thaw cycles.
Hersteller:
Aviva Systems Biology
Typ:
Antibodies: Polyclonal Antibody