BEST1 Antibody
Produktgrößen
50ul
£264,00
OAAN01483-50UL
100ul
£379,00
OAAN01483-100UL
200ul
£581,00
OAAN01483-200UL
Über dieses Produkt
- SKU:
- OAAN01483
- Zusätzliche Namen:
- ARB; BMD; BEST; RP50; VMD2; TU15B; Best1V1Delta2
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2); also known as Best macular dystrophy; in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.
- Gendetails:
- bestrophin 1
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human BEST1
- Isotyp:
- IgG
- Molekulargewicht:
- 67 kDa
- Proteindetails:
- Bestrophin-1
- Aufreinigung:
- Affinity purified against immunogen
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php