CFI Antibody
Produktgrößen
50ul
£264,00
OAAN01399-50UL
100ul
£379,00
OAAN01399-100UL
200ul
£581,00
OAAN01399-200UL
Über dieses Produkt
- SKU:
- OAAN01399
- Zusätzliche Namen:
- FI; IF; KAF; AHUS3; ARMD13; C3BINA; C3b-INA
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- This gene encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains; which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b; and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency; an autosomal recessive disease associated with a susceptibility to pyogenic infections. Mutations in this gene have been associated with a predisposition to atypical hemolytic uremic syndrome; a disease characterized by acute renal failure; microangiopathic hemolytic anemia and thrombocytopenia. Primary glomerulonephritis with immune deposits and age-related macular degeneration are other conditions associated with mutations of this gene.
- Gendetails:
- complement factor I
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human CFI
- Isotyp:
- IgG
- Molekulargewicht:
- 66 kDa
- Proteindetails:
- Complement factor I
- Aufreinigung:
- Affinity purified against immunogen
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php