CSF1R Antibody
Produktgrößen
50ul
£264,00
OAAN01017-50UL
100ul
£379,00
OAAN01017-100UL
200ul
£581,00
OAAN01017-200UL
Über dieses Produkt
- SKU:
- OAAN01017
- Zusätzliche Namen:
- FMS; CSFR; FIM2; HDLS; C-FMS; CD115; CSF-1R; BANDDOS; M-CSF-R
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- The protein encoded by this gene is the receptor for colony stimulating factor 1; a cytokine which controls the production; differentiation; and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL); HL cell lines and anaplastic large cell lymphoma.
- Gendetails:
- colony stimulating factor 1 receptor
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human CSF1R
- Isotyp:
- IgG
- Molekulargewicht:
- 108 kDa
- Proteindetails:
- Macrophage colony-stimulating factor 1 receptor
- Aufreinigung:
- Affinity purified
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20°C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php