DDB2 Antibody
Produktgrößen
50ul
£264,00
OAAN00570-50UL
100ul
£379,00
OAAN00570-100UL
200ul
£581,00
OAAN00570-200UL
Über dieses Produkt
- SKU:
- OAAN00570
- Zusätzliche Namen:
- XPE; DDBB; UV-DDB2
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair; and this complex mediates the ubiquitylation of histones H3 and H4; which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E; a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development; in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.
- Gendetails:
- damage specific DNA binding protein 2
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human DDB2
- Isotyp:
- IgG
- Molekulargewicht:
- 48 kDa
- Proteindetails:
- DNA damage-binding protein 2
- Aufreinigung:
- Affinity purified against immunogen
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php