DCTN1 Antibody
Produktgrößen
50ul
£264,00
OAAN00530-50UL
100ul
£379,00
OAAN00530-100UL
200ul
£581,00
OAAN00530-200UL
Über dieses Produkt
- SKU:
- OAAN00530
- Zusätzliche Namen:
- P135; DP-150; DAP-150
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- This gene encodes the largest subunit of dynactin; a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions; including ER-to-Golgi transport; the centripetal movement of lysosomes and endosomes; spindle formation; chromosome movement; nuclear positioning; and axonogenesis. This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA).
- Gendetails:
- dynactin subunit 1
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human DCTN1
- Isotyp:
- IgG
- Molekulargewicht:
- 142 kDa
- Proteindetails:
- Dynactin subunit 1
- Aufreinigung:
- Affinity purified against immunogen
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php