FKBP1A Antibody
Produktgrößen
50ul
£264,00
OAAN00515-50UL
100ul
£379,00
OAAN00515-100UL
200ul
£581,00
OAAN00515-200UL
Über dieses Produkt
- SKU:
- OAAN00515
- Zusätzliche Namen:
- FKBP1; PKC12; PKCI2; FKBP12; PPIASE; FKBP-12; FKBP-1A
- Klonalität:
- Polyclonal
- Konjugat:
- Unconjugated
- Weitere Details:
- The protein encoded by this gene is a member of the immunophilin protein family; which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels; and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse; deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants; encoding the same protein; have been identified. The human genome contains five pseudogenes related to this gene; at least one of which is transcribed.
- Gendetails:
- FK506 binding protein 1A
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human FKBP1A
- Isotyp:
- IgG
- Molekulargewicht:
- 12 kDa
- Proteindetails:
- Peptidyl-prolyl cis-trans isomerase FKBP1A
- Aufreinigung:
- Affinity purified against immunogen
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Polyclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php