BAG4 Antibody
Produktgrößen
100 ug
£582,00
OAAL00462-100UG
Über dieses Produkt
- SKU:
- OAAL00462
- Zusätzliche Namen:
- BAG family molecular chaperone regulator 4;BAG-4;BCL2 associated athanogene 4;bcl-2-associated athanogene 4;silencer of death domains;SODD.
- translate.label.attr.clone:
- 2G9
- Klonalität:
- Monoclonal
- Weitere Details:
- The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2; Raf-protein kinase; steroid hormone receptors; growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus; which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3); and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. [provided by RefSeq
- Gendetails:
- BAG cochaperone 4
- Host:
- Mouse
- Immunogen:
- BAG4 (AAH38505; 1 a.a. ~ 457 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Isotyp:
- IgG2a Kappa
- Proteindetails:
- BCL2-associated athanogene 4 [Homo sapiens]|Homo sapiens BCL2-associated athanogene 4; mRNA (cDNA clone MGC:33671 IMAGE:5259771); complete cds
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php