GRN Antibody
Produktgrößen
100 ug
£582,00
OAAL00128-100UG
Über dieses Produkt
- SKU:
- OAAL00128
- Zusätzliche Namen:
- acrogranin;CLN11;epithelin;GEP;glycoprotein 88;glycoprotein of 88 Kda;GP88;granulin-epithelin;granulins;PC cell-derived growth factor;PCDGF;PEPI;PGRN;proepithelin;progranulin.
- translate.label.attr.clone:
- 1A8
- Klonalität:
- Monoclonal
- Weitere Details:
- Granulins are a family of secreted; glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein; progranulin; is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active; 6 kDa peptides. These smaller cleavage products are named granulin A; granulin B; granulin C; etc. Epithelins 1 and 2 are synonymous with granulins A and B; respectively. Both the peptides and intact granulin protein regulate cell growth. However; different members of the granulin protein family may act as inhibitors; stimulators; or have dual actions on cell growth. Granulin family members are important in normal development; wound healing; and tumorigenesis. [provided by RefSeq
- Gendetails:
- granulin precursor
- Host:
- Mouse
- Immunogen:
- GRN (NP_002078; 494 a.a. ~ 593 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Isotyp:
- IgG2a Kappa
- Proteindetails:
- granulins precursor [Homo sapiens]|Homo sapiens granulin precursor (GRN); mRNA
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
- Hersteller:
- Aviva Systems Biology
- Typ:
- Antibodies: Monoclonal Antibody
- Datenblatt des Herstellers:html_datasheet.php